AustralieFrV1, Main, Exploration, bibRecord, 008E88

Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana

Identifieur interne : 008E88 ( Main/Exploration ); précédent : 008E87; suivant : 008E89

Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana

Auteurs : Jérome Appenzeller [France] ; Ghezala Mihci [France] ; Marie-Thérèse Martin [France] ; Jean-Francois Gallard [France] ; Jean-Louis Menou ; Nicole Boury-Esnault [France] ; John Hooper [Australie] ; Sylvain Petek [France] ; Severine Chevalley [France] ; Alexis Valentin [France] ; Anne Zaparucha [France] ; Ali Al-Mourabit [France] ; Cécile Debitus [France]

Source :

Journal of natural products : (Print) [ 0163-3864 ] ; 2008.

RBID : Pascal:08-0502079

Descripteurs français

Pascal (Inist)
- Iles Salomon, Milieu marin, Eponge, Porifera, Isolement, Analyse structurale, Alcaloïde, Diterpène, Activité biologique, Antipaludique, Plasmodium falciparum, In vitro, Origine animale, Terpénoïde, Pharmacognosie, Cation organique, Antiparasitaire, Antiprotozoaire, Agelas, Agelasine J, Agelasine K, Agelasine L, Agelas mauritiana, Purinium composé, Clérodane dérivé.
Wicri :
- topic : Milieu marin.

English descriptors

KwdEn :
- Alkaloid, Animal origin, Antimalarial, Antiprotozoal agent, Biological activity, Diterpene, In vitro, Isolation, Marine environment, Organic cation, Parasiticide, Pharmacognosy, Plasmodium falciparum, Porifera, Solomon Islands, Sponge, Structural analysis, Terpenoid.

Abstract

Three new diterpene alkaloids, agelasine J (3), agelasine K (4), and agelasine L (5), were isolated from the marine sponge Agelas cf. mauritiana collected in the Solomon Islands. The structures of these compounds were elucidated by physical data analyses. They displayed in vitro antimalarial activity against Plasmodium falciparum.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 003237
to stream PascalFrancis, to step Curation: 002E16
to stream PascalFrancis, to step Checkpoint: 003424
to stream Main, to step Merge: 009838
to stream Main, to step Curation: 008E88

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana</title>
<author><name sortKey="Appenzeller, Jerome" sort="Appenzeller, Jerome" uniqKey="Appenzeller J" first="Jérome" last="Appenzeller">Jérome Appenzeller</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mihci, Ghezala" sort="Mihci, Ghezala" uniqKey="Mihci G" first="Ghezala" last="Mihci">Ghezala Mihci</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gallard, Jean Francois" sort="Gallard, Jean Francois" uniqKey="Gallard J" first="Jean-Francois" last="Gallard">Jean-Francois Gallard</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Menou, Jean Louis" sort="Menou, Jean Louis" uniqKey="Menou J" first="Jean-Louis" last="Menou">Jean-Louis Menou</name>
<affiliation><inist:fA14 i1="02"><s1>IRD, Centre de Nouméa, BPA5</s1>
<s2>Nouméa</s2>
<s3>NCL</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<wicri:noCountry>NCL</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Boury Esnault, Nicole" sort="Boury Esnault, Nicole" uniqKey="Boury Esnault N" first="Nicole" last="Boury-Esnault">Nicole Boury-Esnault</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>CNRS, Station Marine d'Endoume, Rue de la Batterie des Lions</s1>
<s2>13007 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>13007 Marseille</wicri:noRegion>
<placeName><settlement type="city">Marseille</settlement>
<region type="région" nuts="2">Provence-Alpes-Côte d'Azur</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hooper, John" sort="Hooper, John" uniqKey="Hooper J" first="John" last="Hooper">John Hooper</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Queensland Muséum, P.O. Box 3300</s1>
<s2>South Brisbane, Qld, 4101</s2>
<s3>AUS</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>South Brisbane, Qld, 4101</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Petek, Sylvain" sort="Petek, Sylvain" uniqKey="Petek S" first="Sylvain" last="Petek">Sylvain Petek</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>31062 Toulouse</wicri:noRegion>
<placeName><settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chevalley, Severine" sort="Chevalley, Severine" uniqKey="Chevalley S" first="Severine" last="Chevalley">Severine Chevalley</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Valentin, Alexis" sort="Valentin, Alexis" uniqKey="Valentin A" first="Alexis" last="Valentin">Alexis Valentin</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zaparucha, Anne" sort="Zaparucha, Anne" uniqKey="Zaparucha A" first="Anne" last="Zaparucha">Anne Zaparucha</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Gif-sur-Yvette</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Al Mourabit, Ali" sort="Al Mourabit, Ali" uniqKey="Al Mourabit A" first="Ali" last="Al-Mourabit">Ali Al-Mourabit</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Gif-sur-Yvette</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Debitus, Cecile" sort="Debitus, Cecile" uniqKey="Debitus C" first="Cécile" last="Debitus">Cécile Debitus</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">08-0502079</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 08-0502079 INIST</idno>
<idno type="RBID">Pascal:08-0502079</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">003237</idno>
<idno type="wicri:Area/PascalFrancis/Curation">002E16</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">003424</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">003424</idno>
<idno type="wicri:doubleKey">0163-3864:2008:Appenzeller J:agelasines:j:k</idno>
<idno type="wicri:Area/Main/Merge">009838</idno>
<idno type="wicri:Area/Main/Curation">008E88</idno>
<idno type="wicri:Area/Main/Exploration">008E88</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana</title>
<author><name sortKey="Appenzeller, Jerome" sort="Appenzeller, Jerome" uniqKey="Appenzeller J" first="Jérome" last="Appenzeller">Jérome Appenzeller</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mihci, Ghezala" sort="Mihci, Ghezala" uniqKey="Mihci G" first="Ghezala" last="Mihci">Ghezala Mihci</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gallard, Jean Francois" sort="Gallard, Jean Francois" uniqKey="Gallard J" first="Jean-Francois" last="Gallard">Jean-Francois Gallard</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Menou, Jean Louis" sort="Menou, Jean Louis" uniqKey="Menou J" first="Jean-Louis" last="Menou">Jean-Louis Menou</name>
<affiliation><inist:fA14 i1="02"><s1>IRD, Centre de Nouméa, BPA5</s1>
<s2>Nouméa</s2>
<s3>NCL</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<wicri:noCountry>NCL</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Boury Esnault, Nicole" sort="Boury Esnault, Nicole" uniqKey="Boury Esnault N" first="Nicole" last="Boury-Esnault">Nicole Boury-Esnault</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>CNRS, Station Marine d'Endoume, Rue de la Batterie des Lions</s1>
<s2>13007 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>13007 Marseille</wicri:noRegion>
<placeName><settlement type="city">Marseille</settlement>
<region type="région" nuts="2">Provence-Alpes-Côte d'Azur</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hooper, John" sort="Hooper, John" uniqKey="Hooper J" first="John" last="Hooper">John Hooper</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Queensland Muséum, P.O. Box 3300</s1>
<s2>South Brisbane, Qld, 4101</s2>
<s3>AUS</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>South Brisbane, Qld, 4101</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Petek, Sylvain" sort="Petek, Sylvain" uniqKey="Petek S" first="Sylvain" last="Petek">Sylvain Petek</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>31062 Toulouse</wicri:noRegion>
<placeName><settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chevalley, Severine" sort="Chevalley, Severine" uniqKey="Chevalley S" first="Severine" last="Chevalley">Severine Chevalley</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>31062 Toulouse</wicri:noRegion>
<placeName><settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Valentin, Alexis" sort="Valentin, Alexis" uniqKey="Valentin A" first="Alexis" last="Valentin">Alexis Valentin</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>31062 Toulouse</wicri:noRegion>
<placeName><settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zaparucha, Anne" sort="Zaparucha, Anne" uniqKey="Zaparucha A" first="Anne" last="Zaparucha">Anne Zaparucha</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Al Mourabit, Ali" sort="Al Mourabit, Ali" uniqKey="Al Mourabit A" first="Ali" last="Al-Mourabit">Ali Al-Mourabit</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Institut de Chimie des Substances Naturelles du CNRS, Avenue de la Terrasse</s1>
<s2>91198 Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
<wicri:noRegion>Avenue de la Terrasse</wicri:noRegion>
<wicri:noRegion>91198 Gif-sur-Yvette</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Debitus, Cecile" sort="Debitus, Cecile" uniqKey="Debitus C" first="Cécile" last="Debitus">Cécile Debitus</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>UMR 152 IRD-Université Paul Sabotier Toulouse 111, Faculté des Sciences Pharmaceutiques</s1>
<s2>31062 Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>31062 Toulouse</wicri:noRegion>
<placeName><settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of natural products : (Print)</title>
<title level="j" type="abbreviated">J. nat. prod. : (Print)</title>
<idno type="ISSN">0163-3864</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of natural products : (Print)</title>
<title level="j" type="abbreviated">J. nat. prod. : (Print)</title>
<idno type="ISSN">0163-3864</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alkaloid</term>
<term>Animal origin</term>
<term>Antimalarial</term>
<term>Antiprotozoal agent</term>
<term>Biological activity</term>
<term>Diterpene</term>
<term>In vitro</term>
<term>Isolation</term>
<term>Marine environment</term>
<term>Organic cation</term>
<term>Parasiticide</term>
<term>Pharmacognosy</term>
<term>Plasmodium falciparum</term>
<term>Porifera</term>
<term>Solomon Islands</term>
<term>Sponge</term>
<term>Structural analysis</term>
<term>Terpenoid</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Iles Salomon</term>
<term>Milieu marin</term>
<term>Eponge</term>
<term>Porifera</term>
<term>Isolement</term>
<term>Analyse structurale</term>
<term>Alcaloïde</term>
<term>Diterpène</term>
<term>Activité biologique</term>
<term>Antipaludique</term>
<term>Plasmodium falciparum</term>
<term>In vitro</term>
<term>Origine animale</term>
<term>Terpénoïde</term>
<term>Pharmacognosie</term>
<term>Cation organique</term>
<term>Antiparasitaire</term>
<term>Antiprotozoaire</term>
<term>Agelas</term>
<term>Agelasine J</term>
<term>Agelasine K</term>
<term>Agelasine L</term>
<term>Agelas mauritiana</term>
<term>Purinium composé</term>
<term>Clérodane dérivé</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Milieu marin</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Three new diterpene alkaloids, agelasine J (3), agelasine K (4), and agelasine L (5), were isolated from the marine sponge Agelas cf. mauritiana collected in the Solomon Islands. The structures of these compounds were elucidated by physical data analyses. They displayed in vitro antimalarial activity against Plasmodium falciparum.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
</country>
<region><li>Midi-Pyrénées</li>
<li>Occitanie (région administrative)</li>
<li>Provence-Alpes-Côte d'Azur</li>
</region>
<settlement><li>Marseille</li>
<li>Toulouse</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Menou, Jean Louis" sort="Menou, Jean Louis" uniqKey="Menou J" first="Jean-Louis" last="Menou">Jean-Louis Menou</name>
</noCountry>
<country name="France"><noRegion><name sortKey="Appenzeller, Jerome" sort="Appenzeller, Jerome" uniqKey="Appenzeller J" first="Jérome" last="Appenzeller">Jérome Appenzeller</name>
</noRegion>
<name sortKey="Al Mourabit, Ali" sort="Al Mourabit, Ali" uniqKey="Al Mourabit A" first="Ali" last="Al-Mourabit">Ali Al-Mourabit</name>
<name sortKey="Boury Esnault, Nicole" sort="Boury Esnault, Nicole" uniqKey="Boury Esnault N" first="Nicole" last="Boury-Esnault">Nicole Boury-Esnault</name>
<name sortKey="Chevalley, Severine" sort="Chevalley, Severine" uniqKey="Chevalley S" first="Severine" last="Chevalley">Severine Chevalley</name>
<name sortKey="Debitus, Cecile" sort="Debitus, Cecile" uniqKey="Debitus C" first="Cécile" last="Debitus">Cécile Debitus</name>
<name sortKey="Gallard, Jean Francois" sort="Gallard, Jean Francois" uniqKey="Gallard J" first="Jean-Francois" last="Gallard">Jean-Francois Gallard</name>
<name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<name sortKey="Mihci, Ghezala" sort="Mihci, Ghezala" uniqKey="Mihci G" first="Ghezala" last="Mihci">Ghezala Mihci</name>
<name sortKey="Petek, Sylvain" sort="Petek, Sylvain" uniqKey="Petek S" first="Sylvain" last="Petek">Sylvain Petek</name>
<name sortKey="Valentin, Alexis" sort="Valentin, Alexis" uniqKey="Valentin A" first="Alexis" last="Valentin">Alexis Valentin</name>
<name sortKey="Zaparucha, Anne" sort="Zaparucha, Anne" uniqKey="Zaparucha A" first="Anne" last="Zaparucha">Anne Zaparucha</name>
</country>
<country name="Australie"><noRegion><name sortKey="Hooper, John" sort="Hooper, John" uniqKey="Hooper J" first="John" last="Hooper">John Hooper</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 008E88 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 008E88 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:08-0502079
   |texte=   Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les relations entre la France et l'Australie

Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana

Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri